The war with Iran will likely end with one of two outcomes—each leading the Middle East down a very different path.
Either the US-Israeli campaign will devastate the Iranian regime to the point where the Iranian people rise up and change the regime, or the conflict will end without a decisive outcome and the regime will somehow manage to survive.
If the regime survives, the reality for Israel and the region will remain largely the same as it has been since 1979. Iran will continue to threaten Israel and project power through its network of proxies across the Middle East. Arab countries will continue balancing between confronting Iranian influence while also maintaining their traditional hostility toward Israel.
Let us also not be naïve. In some parts of the Arab world there are leaders and movements that prefer such an outcome, because the continued existence of the Iranian threat allows them to preserve their longstanding hostility toward Israel and the Jewish people while avoiding deeper regional cooperation.